Story 10 · Genes and medicine

The man who could learn a skill but not remember learning it

After brain surgery in 1953, Henry Molaison could no longer form new long-term memories of events, yet he could still improve at new skills, which showed that the brain has separate memory systems.

  • Henry Molaison (patient H.M.)
  • Hartford, Connecticut, and Montreal, Canada
  • 1957
  • 3 min read
On this page
Before you readWhat would you do?

Yesterday you gave a chatbot all the details of your project. Today you open a new chat and ask it to continue, and it seems to know nothing. What is the most likely explanation, and what should you do?

Pick an answer now. The file tells you whether you were right.

01The file in one minute

  1. 1The surgery

    In 1953 surgery for severe epilepsy removed most of Henry Molaison's hippocampus on both sides.

  2. 2The loss

    He could no longer form new long-term memories of events, though older memories and short-term memory remained.

  3. 3The surprise

    He improved at mirror drawing over days without remembering practising, showing memory has separate systems.

  4. 4The lesson for AI

    Many chatbots use only the current chat. Give key facts again in a new chat.

02Timeline

  1. 1953

    William Scoville operates on Henry Molaison to treat his epilepsy.

  2. 1957

    Scoville and Brenda Milner describe his memory loss.

  3. 1960s onward

    Researchers including Suzanne Corkin study him for decades.

  4. 2008

    Molaison dies, and his name is made public.

03The story

Henry Molaison had severe epilepsy that medicines could not control. In 1953, aged 27, he had surgery by the neurosurgeon William Scoville, who removed parts of the inner temporal lobes on both sides of his brain, including most of the hippocampus. His seizures became less severe.

But Molaison could no longer form new long-term memories of facts and events. He could hold a conversation and keep a number in mind for a short time, then forget it once distracted. He could still remember much of his life from before the surgery. In research papers he was known only as H.M. to protect his privacy.

The psychologist Brenda Milner studied him and, with Scoville, described his memory loss in 1957. In one famous task, he practised tracing a star while looking only at its reflection in a mirror. He improved over several days, while saying each time that he had never done it before. Researchers, including Suzanne Corkin, studied him for decades. He died in 2008, and his name was then made public.

04What the science says

His case showed that memory is several systems. The hippocampus is essential for forming new memories of facts and events, but short-term memory and learning motor skills can work without it. The surgery also taught doctors to avoid removing both hippocampi.

The AI angle: chatbots have something like Molaison's pattern. Within one conversation they can use what you said, but many forget it when a new chat starts, and they do not learn from your chat unless the tool is built to save it.

The idea behind this caseLesson: The context window: AI's short-term memory →

Kit the fox, ManuAI's guide, thinking it over

05What to take from it

  1. Remember that memory has different parts, and losing one does not mean losing all.
  2. Do not expect a chatbot to remember a previous conversation unless the tool clearly says it does.
  3. Put the key facts in each new chat, or in a saved note, when you need the AI to use them.
  4. If you or a relative have new, worsening memory problems, see a doctor, since many causes can be treated.
Yesterday you gave a chatbot all the details of your project. Today you open a new chat and ask it to continue, and it seems to know nothing. What is the most likely explanation, and what should you do?

06 — Would you have caught it?

Yesterday you gave a chatbot all the details of your project. Today you open a new chat and ask it to continue, and it seems to know nothing. What is the most likely explanation, and what should you do?

07 — Sources

  1. Loss of recent memory after bilateral hippocampal lesions · Journal of Neurology, Neurosurgery & Psychiatry · 1957-02
  2. Henry Molaison · Wikipedia · 2024